If you're hunting whitetail, I highly recomend using 140 eldms. Most 6.5 creeds shoot extremely well with factory hornady ammo too. When reloading, even better.
For deer sized game I am all about using explosive bullets. Explosive, or frangible non-bonded thin jacketed cup and core bullets leave massive wound channels. These massive wound channels help make up for less than ideal shots. If all of our shots were perfect then non-expanding bullets would be perfect. The reality is, not all shots are perfect.
Where I hunt whitetail deer in south texas, having deer run farther than 20-30 yards is terrible. Thick brush and cactus where you have to crawl through parts to find your animal is not much fun. Myself, along with family members have had much better luck with frangible bullets than partitions, eldxs, and solid copper bullets.