I've been running a 28 for a while, shot a lot of bullets but I kill mostly elk so pretty much what ever I shoot for elk does great on deer but not everything that is great on deer will be ideal for elk if that makes sense. I do shoot the Barnes for deer and smaller game but will never use them on elk again after years of using them, the 145 will work well on deer I MUCH prefer the Hammers because they cause a way better permanent wound channel and they tune soooo much easier for accuracy, just a better bullet period but just about anything will kill a deer. I shoot mostly 195 Bergers and 177 Hammers in my 28 but that's more bullet than needed for deer but if you want to go light for cal on bullets I would not shoot the Berger because you'll be outside their ideal window.