My 18 year old son and I each have a 300 RUM that we use to hunt mule deer and elk in Utah. Both rifles have heavy fluted sendero barrels with suppressors (we use muzzle brakes at times too). The felt recoil with either the muzzle brake or suppressor is very manageable, however, I prefer hunting with a suppressor because I can do so either with light or no earplugs.
We shoot 185 gr or 210 gr Burger VLD Hunting bullets with around 92 gr to 90 gr of powder.
When I got the first 300 RUM, it had a light sporter barrel, wood stock and no muzzle break. I had to use my son's lacrosse shoulder pads to shoot it! Essentially, the rifle was unusable for me. Once I rebarrled the rifle and installed a muzzle break, the felt recoil became very manageable and the rifle was very easy to shoot. However, the muzzle break deflects the sound toward the shooter and I damaged my left ear permanently (it is ringing as I type). The suppressor fixed the sound problem without materially changing the felt recoil.
The rifles are heavy. We don't use horses or ATV's to get where we hunt. We carry them a long way in steep terrain. However, the rifles are very accurate and can take significant abuse. We are extremely confident with them out to 1,000 yards or more in all types of weather conditions. We would not trade these rifles for something that is lighter.