I had the same thing happen to me last year with a 300 RUM, and a 168 VLD. Velocity was at 3369, distance was 219 yards. Huge flesh wound. Knocked the deer down, but when I went to recover her later, she " recovered" enough to get up and disappear into the woods. Lots of blood, but she covered a lot of ground, and we did not find her. That was the last Berger bullet I have used for hunting.
I switched to Barnes LRX, and TSX , and Nosler Partition. I used the LRX this past season, and am VERY impressed. Total penetration, and great terminal performance.
As I've said before, I'm a big fan of the Nosler Partition but I will be experimenting with the 168gr LRX this off season. I prefer complete penetration as the vast majority of animals I've killed have gone a little distance after a lung hit and required some tracking. I like the blood trail that an exit wound gives, which is important when there is no snow on the ground. I also want the ability to break heavy bone and keep on penetrating.