You can hit an intended target with a canted rifle. To do it with "precision" as in repeatable X ring groups is another story. But ... you've got to adjust the scope to account for the cant angle. When you fire the rifle a bullet exits the muzzle. The relationship between the various elements (muzzle relationship to the target, how the rifle's recoil affects muzzle movement and applicable ballistics data) determines where the bullet will go. Theoretically, you could roll the rifle over on its side and still hit a target, with some degree of accuracy, using the scope to line up the shot. But you'd have to know how to accommodate all of the physics involved.
Consider this. You can fire a rocket into space toward the position that the moon will be in when the rocket arrives. But, in the interim, the rocket's trajectory will not be in direct alignment with the moon's position.
All that being said, forget about hunting with a canted rifle. The results will not be what you expect based on a properly aligned rifle and scope.