I've never used one on Alaskan moose, and never plan to. The primary advantages to a Berger VLD is their target grade accuracy and high BC for long range hunting - where retained long range energy and velocity, reduced wind drift, and pinpoint accuracy are required.
The kill zone on a moose is huge, and you're unlikely to need any of those bullet properties to kit the lungs. You shouldn't need to worry about shooting 1" groups at 250 yards on an animal the size of a moose. Unless you purposely intend to set up for a 500 plus yard shot, I would shoot something like a Nosler Accubond or Partition or Nosler's all copper bullet. Or a Swift Scirocco or A-frame. Even a Speer Trophy Bonded Bear Claw, or some other bonded lead core bullet. Or you could go lead free with a Barnes TSX. These bullets are all reliable killers under 500 yards, and if you do happen to hit a meaty or muscular area, they'll damage less meat and help ensure more reliable penetration to the vitals.
If you do decide to hunt with the Berger VLD because you're married to them, or your expect, or plan on, a 500 plus yard shot, I recommend waiting for the perfect broadside exposure, and then punch it into the lungs just behind the front shoulder muscles. He'll probably run 50 yards, certainly less than 100, stop and lower his head while losing strength, and then bed down or collapse. Alaskan moose don't seem to go down as if struck by lightning unless their hit in the head, neck, or the spine. But they don't go very far when double-lunged with a sharp broadhead or an expanding bullet.