When a Mil reticle is used for range finding it does simplify the calculations a little as the width 1 mil subtends is exactly 1/1000 of the distance to the target. Thats the only reason Mils are used. When a laser range finder is used the only benefit of either system is what a person is comfortable using. In either case for precise shooting you need fractional markings or adjustments. 1/4 MOA adjustments are comfortable. 1/10 Mil adjustments are comfortable. Maybe half that for benchrest shooting.

All reticle systems are a trade off of speed and adaptability A simple "target dot" reticle with target knobs is very adaptable, but it is slow requiring turning knobs and counting clicks. A custom reticle calibrated for drop and windage is very fast, and requires no knob twiddling, but it can only match one bullet at one velocity at one elevation angle in one atmospheric density. You also have to interpolate between the markings which is an additional source of error. Other reticles lie somewhere in between for speed and precision.

In the future high resolution LCD displays may replace a fixed reticle. They could automatically be generated based on range finder, inclinometer, and atmospheric measurements. Until then whatever reticle you pick will be a compromise and will require computations, either mental, lookup table, or calculator.

One additional choice is to make only "point blank" shots relying on a flat trajectory. Wind has to be light too but it can work to over 300 yards with the right selection of cartridge and bullet.