117 Sierra Pro Hunter hands down for deer. I have used the 25-06 for around 20 years to shoot hundreds of deer as a crop damage controller with my buddy which also uses a bunch of different 25's from the Bob through the Weatherby. We have both used many different bullets and both have come to the conclusion that most will do but for overall accuracy and terminal performance and COST the 117 Sierra Pro Hunter wins hands down.
Work up to these but these loads shoot well in most 25-06s.
52 grs H4831 or the SC version. CCI BR2 primer, Rem. case, 117 Sierra and load them to start with 20 thousands off the lands which is usually the sweet spot.
49 grs IMR or AA 4350, Rem case, CCI 250 primer, 117 Sierra, 20 thousands off the lands.
We have killed hundreds of deer out to around 550 yards and if you place the 117 Sierra in the shoulder of a deer around 99% of the time where it was standing is where you will find it dead. BANG FLOP.