I have had A LOT of experience with this pill and caliber! Actually, just got back from the range shooting a bunch of them. The rifle (my wifes) is a Weatherby Vanguard .243 and it LOVES the 105's (NOT the 1:8 twists though). I set it on top of 36gr Varget, seat out .001 from the lands, and it will get MOA accuracy at 100yds all day long. Took me a while to get my seating depth just right since the Weatherby has so much freebore, but once I hit the "magic COAL", groups tightened right up and they have proved to be VERY reliable and consistent. What type of rifle are you using? Sometimes, the 1:8's will work for a particular rifle, but in mine, they don't shoot very well. All in all, it's a fine bullet and very easy to load with. I would recommend it highly to you if you want to gain more in terminal ballistics. Good luck.
TH