I load some pretty consistent ammo for my 6.5 Grendel on my Dillon 550 using extruded small powder. The only thing that I was cautions of was case length, I sized a few and measured, they were still short enough. I may have chamfered and debarred. I can't remember, but I probably did. When setting the powder measurer I was weighing charges and they were all at least with in 0.1gr of where I wanted to be, with most being dead on. When working with something like that having a bigger node that can go from say 26.7 to 27.0 would be ideal.
Now, some of the other stuff I load, it'll never see a progressive, but I'm running large sticks of powder through those so I wouldn't be confident in the Dillon to measure those out very well.