We go coyote hunting with my friends 50 Barret 6X24 nightforce scope. I have some friends that used the 50 for elk & deer hunting in idaho in years past. The problem is some states have banned the .50 BMG round. Some states allow the 50 if you have game type lead spire points.
Three years ago I personally took a nice 4X4 in Potter County Pennsylvania with a 50 cal BMG. HSM 750gr Bore Rider HP at 2700 fps does an excellent job of providing for a humane kill. The animal was literally dead before it hit the ground. I have pictures and will try to post them, but haven't had much luck posting pictures so far.