Weatherby Vanguard, 25-06, 1/10 twist. Less than a year into reloading, I shot (100 yards) my much anticipated deer load using a 115 grain Nosler Partition. Most will know the Partition is a premium big game bullet, considered by many to be one of the best. What a disappointment. About the best I could get was 2"+ to 2.5" group, and it threw them about 2" high and 2" left. I tried several different powder charges, 47,48 and 49 (max) grains of IMR4350 which is a go-to powder for the 25-06. No charge performed better than any other, all equally bad. So obviously, this gun doesn't like the 115 grain Nosler Partition. **I will add the barrel had heated up pretty good by the time I shot this load. However, I shot another load with a hot barrel(120 gr. Speer BTSP) that performed well enough to hunt and shows promise of doing better. My questions: 1. Should I abandon this bullet altogether or is there a possibility of dramatic improvement using a different powder? I've never loaded anything that shot this badly 2. I shot several groups of just a hair over 1" using a 120 grain Speer BTSP. Would moving up to a 120 grain Partition make much difference or would it be best to continue experimenting with the Speer and, again, just forget the Partition altogether? I'm not hung up on the Nosler Partition, just that it is considered a very effective hunting bullet. Some have no hesitation using the 25-06 for elk with the Partition, and do it effectively. But I don't want to spend a lot of time trying different combos, on an EXPENSIVE bullet, if there is little chance of "hitting the sweet spot" and finding the magic combination.