You will be okay using 150 grain data. As always, use starting loads and work up. I've had great luck with Retumbo in my 270 WSM shooting 150 grain bullets. I've also seen good results with MagPro in a different rifle shooting 140s and 150s. I have read reports of good accuracy with H1000 and H4831SC with 140-150 grain bullets although I haven't tested these powders myself. If you're chasing high velocity I'd recommend MagPro. There seems to be an accuracy node with this powder at 3100-3200 fps. My current rifle can't quite reach that with the bullets I'm shooting and I wasn't able to get good accuracy. I tried Retumbo and it shot fantastic so I didn't test anything beyond that.