Smokeless muzzle loaders can do it with the right bullet sabot powder combo. I would recommend the savage 10ml2. The problem I run into is that when I am hunting it is difficult to keep my powder dry for long periods. My barrel heats up when I bring it in the truck and cools when I bring it outside causing condensation in the barrel. I would need to fire the gun several times per day to guarantee the type of accuracy needed for a long shot. Our deer muzzle loader season is three weeks long and I would go through a lot of ammo. If you are in a dry climate you may have better luck. Doug's message boards has many guys who have been using very high performance muzzle loaders for a long time, and I doubt many of them have spent anything close to that for a gun. The savages seam to be very impressive weapons capable of much higher pressure and velocity compared to standard in line muzzle loaders, and you can replace the barrels to change caliber twist etc. the same as any other savage rifle. If you decide you don't like the factory barrel you can call Pac-Nor and get a great barrel to your specs. Loosen barrel nut screw on new barrel tighten nut done. More of the barrel manufacturers are making aftermarket barrels for the 10ml2 every year. A good friend of mine had a custom muzzle loader built on a rem 700 action, the problem with that gun was that he needed to load the primers into brass that needed to be cut and sized very accurately. Carrying them in his pocket they would get dinged up and would not shoot well. He struggled with it for a few years then put a 308 barrel on it and uses it as a rifle.