Extended range is extended range whether talking about a 22 LR or 33 Nosler, not every caiber is the same. And inside ever caliber the actual chambering will make a big difference! How much energy do like to see on impact at max range for that chambering? Personally I set mine at 1,000 ft lbs. What ever chambering I'm shooting must have near that for me to take the shot. The 6.5 Grendel is the cartridge at the center of the discussion. Most of the guys are shooting gas guns (myself included) so that takes a little more away from the down range effectiveness of those bullets. I've recently been engaged in several discussions where guys are taking shot where they only have 500 ft lbs of energy on impact. IMO - that is not enough! What is your take on bullet energy at Long ranges?