May not be what you want to here, but that does not tell me anything without knowing a little more information.
The only thing I would do after I have come up with the best group with the bullet and powder combination is to begin experimenting with bullet seating depth off the lands. I follow the method as recommended by Berger. Usually works to achieve best accuracy.
After all that and still not satisfied, then start the process over with a different bullet and powder combination until you fin what the gun likes bes