If you look at a brake, the ports will direct the gasses at an angle. Some brakes have top ports too.
Think of the barrel, with the top at 0°. Top ports should eject exactly at 0°, side ports at 90° and 270°.
Timing is so the threads of your barrel end and the brake line up so your angles are exact above when the brake is bottomed to the barrel end and tightened to 30 ft-lbs (or whatever the recommended torque is.)
If your timing is off, the recoil may push your barrel end one way or the other. For example, if you have a 4 port brake with top holes, being off 5° CW from the shooter's view will push your muzzle to the left as the bullet exits.
Will it affect accuracy? Can't say. I bought a used rifle with a poorly timed brake and at 100 I never found any accuracy issues. On my LR rifles, have gone to great lengths to ensure proper timing.
No idea if these videos are any good: