No, I don't think a "loose" barrel would shoot any better than a premium match grade barrel. If you're having issues with finding a load, I would do a few things before pulling anymore hair out or putting anymore shots down range. I'll list the steps I take to evaluate a poor performing rifle. Trust me, if it can go wrong or cause frustration, it has happened to me. It happens to the best of us.
1- Check to make sure action screws are tight and torqued to 50-65 inch lbs.
2- Check to make sure the scope base and rings are tight and torqued to spec.
3- Check if the barrel is free floating and verify the barrel is free floating when the rifle is rested in the bags like you have been shooting it.
4- Make sure the barrel is clean and doesn't have built up carbon or copper fouling. Borrow or buy a Teslong borescope to make sure of this. They're cheap and awesome.
5- Make sure the bedding is stress free and not binding the action/barrel and check if the internal magazine box is free floating if it has one.
6- Check to make sure there's not built up gunk inside the bolt and in the firing pin spring.
If everything above checks out, I would try a different scope. If that doesn't solve it, then I would just try a different bullet. If you haven't already, run a seating depth test with the components you have been using. Try .010-.050 off in .005 increments with 3 shot groups. If nothing in that test shoots to your liking, then it's time to test new bullets or possibly dive deeper into it and check to make sure the action is getting proper ignition. It's not super common in match grade barrels, but you could potentially have a bad barrel. Before jumping to that conclusion though, I'd first check and try everything I've said above. Report back and ask any questions you have and I'll do my best to help and I'm sure others will chime in too.
Also, I'd like to ask for you to post the build specs on the 280 AI, the components you're using for reloading, and some pictures of the groups it's been shooting. Thank you