This year we can use .22 caliber rifles for Pronghorns in Wyoming. Must be at least 60 grain bullet and the case has to be at least 2 inches. Here's my question...I could only find Hornady 60 grain Hollow points due to the component crunch. I have a .223 and a .22-250. I am leaning toward my coyote rifle which is the .22-250. I have experience with the Hornady bullet shooting them in my AR for High Power competition and they are very accurate for reduced yardage matches. They are flat based so I think you are limited to 200 yards or under which is no problem. I was wondering about the performance on game though....should I load them up hot where a .22-250 excels or should I load them down to not wreak havoc on the meat? I will only take chests shots but sometimes a fast moving bullet can cause blood shot meat up into the shoulder when the small, fast moving bullet expends all of its energy on impact. Dang, I wish I could find a lead tipped bullet. Another source has told me that these bullets perform well on coyotes...going in and ripping up the insides without any fur damage. Sounds good but does anyone have any experience using these bullets on big game?