In my circle I know guys that have taken the 300 to 1300+ on game, the bullet was showing some varied results,but the game was harvested no problem. There are guys on here that favor the 250, it can be pushed fast and look at what they do with 30 cal 230. I shot the majority of my elk with 225 Nosler part. out to the 900 range no problem,some like spine hits where just one and done. I use 300 otm and never feel undergunned for 1000 type.When I used my 7rem I did.I load 250 NAB for my Marine double sharp shooter son in the 340Wby. Has no problems, I h I ave shot a lot of game with the NAB's and like them. In my area here I am seeing more guys using the 300 NAB with good results.The 300 gr. is just a hammer dont care if it is a berger or a NAB.The Nosler seems always easier to get accurate load.