Rooster, no fight just discussion. I carried a .243 for years. I've seen Moose, Caribou, Dall Sheep, Black Bears, and even Brown and Grizzly Bears taken with the .243. And down there I might even try a .243 on Wolves, you guys are only lo9oking to kill one wolf.
Not so here in Alaska. The originator of this thread is also in Alaska, and the references I made were for him, and up here where our Wolves tend to be a bit bigger. Also we look to kill as many Wolves in a pack as we can. Hopefully the entire pack. Last year if you read any of the Wolf Hunting articles in most hunting magazines, you read about Coke Wallace. Coke is a guide who specializes in hunting Wolves. Coke has told me many times to leave anything smaller than a 25-06 at home. The 30-06 will do the job, but is too damaging on fur. In Cokes world the 25-06 is superior. I never claim to be an expert on shooting Wolves, but Coke is, and I will go with his recommendations.
After Coke told me to only bring my 25-06, I sat down and ran the ballistics on all the .25 bullets. The 110gr is the only .25 caliber bullet that retains over 1000 foot pounds of energy beyond 500 yards. We may start shooting at 200 to 300 yards, but by the time the shooting stops we will be shooting out to 500 if not beyond. I shoot a 110gr Nosler Accubond. In the .243 the best retention rate is the 100gr bullet, and it fizzles down to below 1000fps at 360 yards.