I switch barrels, scopes, & stocks all the time. Just make notes for scope settings, & you'll be pretty close, but you'll still need to confirm.
All but two rifles I own have multiple barrels and stocks.
I build off of a "Platform", a platform being a Trigger, action, rings and Scope. Caliber(barrels) are swapped, sometimes stocks.
It is a lot less expensive to have a rack full of barrels vs a rack full of rifles
For shouldered barrels using the same recoil lug, POI does not vary much between the barrels.
Swapping barrels is WAY beyond the scope of most shooters, , and this is a crying shame..
I would be concerned about post #12 damaging the scope internals. I use a torque wrench set at 80 foot/lbs to get a consistent seat of the barrel shoulder on the action. Threads do have an elastic limit where they will stretch.
If you have your barrel channel inletted to the same dia as the barrel shank, you can remove the barrel like you see in post #12. I change out barrels, never remove the scope or stock, but I do it gently so the scope internals are not damaged....4 different calibers on one action/stock/scope, and Trigger.
When I was shooting p. dogs a lot, a barrel vise was welded on the grill guard of my truck. I bore sighted on a p. dog.