I've used and seen used the 300 winmag with the older Barnes 180 XBT. I and a friend found the Barnes to be a real killer on plains game ( 4 hunts in SA & Namibia) I also used a 340W, 35WAI and the 375H&h. I could see no difference int he field for deer/elk sized game. I'm sure the NAB would work swell too. However, I know the Barnes works from any angle in the 300 Win, I imagine it would do even better in the faster 300 BEE. With Banres ( or any mono bullet) faster is always better!