I don't easily offer advice...so this is really an opinion based on personal experience. Move. Take the chance. I live in Arizona... not Phoenix...and life is good. I'm from Indiana and have lived in Massachusetts, Virginia, Alabama, Georgia, Kansas, Nevada, Colorado, Maryland, New Mexico, California, Washington DC,... US Army. The West is a much friendlier place... not the big cities...and there are jobs. Cost of living is lower...not in the big cities. Life is an adventure and everyone resists change but merely existing isn't living. In my rural neighborhood we wave to each other, watch when neighbors go on vacation, help when horses get out, don't put up with city nonsense. Schools are good, 4H is great. Constitutional carry, fishing... I live on the big, beautiful, clear Colorado river... hunting, T-shirts and shorts in January; boats, lakes, and rivers in the summer.
There will be some real adjustments. Arizona is over 3 times the size of Indiana. When I lived across the river in Nevada I could drive 700 miles north...and still be in Nevada. Down the road to the next town can be 2 hrs. Just some examples. Except for the big cities, the west is conservative. We are friendly people, willing to help but don't want neighbors bringing failed politics. Your kids will need to adjust to a more self-relient life style. No whining, no quitting, no excuses.
Overall, from my experience, the western lifestyle... not big cities because big cities are all the same...is good, very good. But not perfect.
Good luck...take a chance.