I've had great results with RL-23 in 243 Win with 95gr VLD, 270 Win with various 150gr, 7mm Rem Mag with various 150gr to 168gr bullets, including Barnes 145gr LRX and 150gr TTSX, and 30-06 with 212gr ELD-X, 215gr Hybrids, 230gr Hybrids and 200gr Barnes.
I bought 8# jugs of RL-23 and RL-16 right when they first came available and after very successful load development in various cartridges in multiple rifles, I bought six more 8# jugs of each. Both powders have been outstanding, for most of my firearms, in appropriate cartridges and with proper bullet weight. Wasn't trying to hoard as both powders were readily available back then. I was just trying to maintain consistency in lot numbers. I've been doing that with powders, bullets, primers and brass, for nearly 40 years now. Down to 16# left of my RL-23...
Incidentally, RL-23 will work in 300 Win Mag with the 212gr to 230gr bullets but, is pretty anemic in that role.