You won't notice much difference in trajectory compared to the heavier bullets until you get past 900 yards. There is only one thing that significantly affects trajectory, and that is time of flight. A 180 grain Accubond and a 215 Berger Hybrid will get to 1000 yards at about the same time so the amount of drop will be roughly the same. The Accubond will reach 500 yards quicker than the Berger so it actually shoots flatter at that distance. You will get more wind drift with the lighter bullet which is the reason many people prefer the heavier, high-BC bullets.
Accuracy shouldn't be an issue. If you're shooting 1/2 MOA at 200 yards you should see the same level of accuracy at longer ranges. You might see greater vertical dispersion if you have a lot of variation in muzzle velocity between shots. Shooting in a variable wind can cause groups to open up as well. But as far as the Accubond itself losing accuracy its not going to happen. The bullets will eventually lose stability but not until they're past 1500 yards.
