Yes, I have used the Remington 9.5M with top loads of RL22 in my .25-06 Sendero with excellent accuracy. I worked up loads for the 100gn Ballistic Tip and Triple Shock and got some one-hole groups with both bullets.
I was pushing the Ballistic Tip over the chronograph at 3300+fps but never checked the TSX. Didn't matter at the time though, it was match-grade accurate and no respecter of whitetails.
I have used them in the .22-250Rem and .243Win, also with excellent accuracy.
Give'em a try. Work up your loads, you may be suprised. JohnnyK.