Love my .300 Rum! I have an extra barrel for it when I burn this one up. I haven't shot much heavier than 180 grain bullets. Recoil is stout but not excessive. I'll stay with the 180's or lighter. Don't know much about the Nosler cartridges. You might need to open the magezine rails a little for a the nosler brass(don't know for sure). The RUM is opened slightly already. I have a 7STW I built with a 27 inch Senduro fluted barrel. Don't really see the need for a 28 Nosler. Maybe if I didn't already have the STW. I say stick with the .300 RUM. Although you might consider a .338 RUM, but make sure it has a muzzle brake. Mine without the brake installed has recoil that is absolutely brutal.