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CWD Now can Infect Humans.
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<blockquote data-quote="Muddyboots" data-source="post: 3087318" data-attributes="member: 63925"><p>There is NO DEFINITIVE causal link to CWD , just data that the person POTENTIALLY consumed deer infected with CWD. Circumstantial at best which in the medical epidemiological CANNOT be stated as definitive.</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/books/NBK507860/[/URL]</p><p></p><p>"CJD may be classified based on the mode of transmission. Sporadic CJD, the most common type (∼85%), is due to misfolding of normal PrP isoforms with no apparent triggers."</p><p></p><p>"Infectious CJD accounts for less than 1% of cases, and it arises from prion transmission by an external source. Subtypes of infectious CJD include <em>kuru</em>, iatrogenic CJD, and variant CJD. <em>Kuru</em> is a disease of Papua New Guinea's Fore people, who consumed the brains of dead relatives as part of ritualistic cannibalism before the practice was banned in the 1950s."</p><p></p><p>"CJD affects about 1 individual per million per year worldwide. Approximately 350 cases are diagnosed annually in the United States. Sporadic CJD is the most common form of human prion disease. The condition has a mean onset age of 62, although it has also been reported in younger and older age groups"</p><p></p><p><strong>"Inherited CJD</strong></p><p></p><p>Genetic CJD has phenotypic variability that may be attributed to the low penetrance of <em>PRNP</em>mutations. Patients with genetic CJD are usually younger than individuals with sporadic CJD, manifesting behavioral and cognitive changes initially, and incoordination and movement abnormalities over the next few months. A family history of similar neurologic manifestations may be elicited.</p><p></p><p>Inherited CJD is fatal, though the duration of illness varies individually. For example, Gerstmann–Straussler–Scheinker syndrome has a slow progression, and death may be delayed for up to 10 years.<a href="https://journals.lww.com/md-journal/fulltext/2021/04230/gerstmann_str_ussler_scheinker_syndrome.99.aspx" target="_blank">[32]</a>"</p><p></p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/books/NBK507860/[/URL]</p></blockquote><p></p>
[QUOTE="Muddyboots, post: 3087318, member: 63925"] There is NO DEFINITIVE causal link to CWD , just data that the person POTENTIALLY consumed deer infected with CWD. Circumstantial at best which in the medical epidemiological CANNOT be stated as definitive. [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/books/NBK507860/[/URL] "CJD may be classified based on the mode of transmission. Sporadic CJD, the most common type (∼85%), is due to misfolding of normal PrP isoforms with no apparent triggers." "Infectious CJD accounts for less than 1% of cases, and it arises from prion transmission by an external source. Subtypes of infectious CJD include [I]kuru[/I], iatrogenic CJD, and variant CJD. [I]Kuru[/I] is a disease of Papua New Guinea's Fore people, who consumed the brains of dead relatives as part of ritualistic cannibalism before the practice was banned in the 1950s." "CJD affects about 1 individual per million per year worldwide. Approximately 350 cases are diagnosed annually in the United States. Sporadic CJD is the most common form of human prion disease. The condition has a mean onset age of 62, although it has also been reported in younger and older age groups" [B]"Inherited CJD[/B] Genetic CJD has phenotypic variability that may be attributed to the low penetrance of [I]PRNP[/I]mutations. Patients with genetic CJD are usually younger than individuals with sporadic CJD, manifesting behavioral and cognitive changes initially, and incoordination and movement abnormalities over the next few months. A family history of similar neurologic manifestations may be elicited. Inherited CJD is fatal, though the duration of illness varies individually. For example, Gerstmann–Straussler–Scheinker syndrome has a slow progression, and death may be delayed for up to 10 years.[URL='https://journals.lww.com/md-journal/fulltext/2021/04230/gerstmann_str_ussler_scheinker_syndrome.99.aspx'][32][/URL]" [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/books/NBK507860/[/URL] [/QUOTE]
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