I run them in my sons 6.5 Creedmoor and my 6.5PRC. Both do the trick on Javelina, coyotes, hogs, whitetails, and mule deer. Also took a couple impala with the 6.5 Creed in Africa and it did the trick there as well. Never more than 1 shot needed and they track well out to 1000 in both rifles...