I have a Remington M700 KS Mountain Rifle in .22/250 with Burris XTR 2-piece bases and Burris Signature Zee rings. Scope is a new Leupold VX3 4.5-14.
I'm assuming the scope is factory centered. Anyway, my first shots at 25 yards are 10 inches low!
I have wound it up a heap to zero it at 100...