I've been shooting the 06AI for about 8 years, And next to my .375 H&H AI it's my favorite cartridge. I currently use 52.5 gr Varget behind a 172gr solid, lake city 1967 brass with cci br4 mag primer to get 3050fps as my pet load. I get an e.s. of about 45 with the varget (wish it were better)...