I built my 22 Creed last year and shot 75 ELDs @ 3400ish with RL22. I thought it was going to be king, but I found I prefer the 53 Vmax @4000 out of my 22-250ai, for the most part. If I was shooting 600+, the the 75's were superior, but under that, I like the 53's best.
I will be loading mainly...