I have seen Remington 700 Sendero bores off center so much that after a gunsmith threaded the muzzle and installed one of his brakes the first shot fired from the rifle with the brake on, the bullet hit the brake and punched a half moon hole in the brake. My discussion with the gunsmith, I said...
Look into the 358 STA I have one you will love it for everything. I have dropped White Tail bucks at 120 and 160 yards. Also have the 35 Whelen 35 Remington. Have built a 35 Whelen AI for a friend of mine very accurate also.