It depends on how accurate and tight you need your groups to be.
As others stated, it's not optimal. But, you may also get lucky.
I was able to work up a load for the 130gr VLD in a 270 that shoots 1.2 MOA in a 1 in 12" barrel where they recommend 1 in 11". It's a really old rifle and I considered that fine for 100-300 yds.
There's another thread running where the guy is getting 12" groups at 100yds and it appears to be partly because his twist is too slow.
I've never experienced anything that bad due to twist. But in at least 2 other situations, I've been stuck at 2 MOA with VLDs and .5 MOA with the right bullets for the twist.
Higher velocity has never worked for me to overcome a slow twist. You can do the math. But, the twist is huge in terms of rpm as compared to adding a few hundred fps. Velocity may however help if you somehow find a sweet spot with the harmonics.
My $.02 is that a lower BC is more predictable than an understabilized bullet.
I no longer waste my time, money, or barrel life on bullets that would most likely be understabilized. ...been there, done that
If you try it, please let us know what you find out.
Thanks!
Richard