I've shot many rounds in past years in both .22-250 and the .220 Swift both for Coyotes and Rock Chucks I found both to be up to the job with out question. But if you have a .220 Swift that running right, it's a phenomenal cartridge. My last .220 Swift was a Remington M700 it was absolutely magic. The Nosler 55gr BT at 3900 fps was laser flat. Many say there's no real difference between the too, however in the field it a very different story, it's kinda like a bumble bee aero dynamically not being able to fly on paper, but in fact'…, it fly's very well. Another field finding of mine; was that my .220 Swift's always seem to be a little more accurate than my .22-250's…. over all. One more myth is that the .220 Swift was a barrel burner, I've shot one pot load of rounds in all the .220 Swift's I had; with proper cleaning care, they shot just has long as my .22 250's or any other high velocity cartridge I hunted with.
So I believe the case I'd pick {between the two} as a long range heavy bullet platform would be the .220 Swift with a 1:6.5 twist barrel 28" inches long using 90gr Sierra MK' or 90gr JLK's.
I'd pick the .220 Swift if I could only have one high velocity Yote rifle with heavy bullets
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