I have glanced through the 6 pages, I'll give my input.
Seems like your ranges start at 400 and go out to as far as your comfortable. If your going to use the hammer bullets, I would definitely go with the heavier option, to reduce wind drift and give you more room for error. Also will likely have more energy, and possibly more retained velocity at the outer limits. I would start your seating either as far as your mag box will allow or somewhere around .020"-.030" off, to give yourself the most room for powder. I have found the hammers to not care where you seat them, in the three guns I have used them in they all shot under half MOA with the first seating depth I tried after a little playing with the powder charge.
You loose some BC with the hammers, but you gain consistent terminal performance. You will be hard pressed to find a bad review of the game performance of the hammers, from point blank out to well over 1000 yds. That simply cannot be said for pretty much any other bullet. There is always someone that has pretty well documented proof of a bullet not performing optimally. Unfortunately, it just happens sometimes, there are hundreds of things that can cause a bullet to not perform right. And that is being expanded due to the higher demands of bullets now days. It is near impossible to find a bullet that will get full penetration at 50 yards through the heavy shoulder of a bull elk without being too destructive, but yet will also get good expansion, full penetration, and put devastating shock on a pronghorn with a broadside through the ribs shot at 1050 yards. From what I have seen, Hammer is the closest one to achieve this of any bullet manufacturer, with the caveat being a lower bc compared to other long range specific bullets. Personally, for my sub 600 yard hunting guns, Hammer is generally my first bullet consideration. For my guns used out to and beyond 1000, I generally look at something with higher bc.