I use IMR 4350 for my 338 wm I load the 225, 250, and 300. All with good results. For the Hornady 225 SXT bullets I use 67gr. with an AOL of 3.337 and have 3 shoot groups at 100 all touching. The 250 are also Hornady SXT bullets which get 67.5 grs. of 4350 with an AOL of 3.363. For my 300 I use Lapuas over 58 grs. with an AOL of 3.363. My next loads of 300 will be the Berger Hybrids I have always had excellent results with Berger bullets I haven't worked up a load yet but hope to in the near future. Hope this helps you out sum but I won't promise you the same results.