I know in a standard 26" 22-250 my accuracy load was getting 4160 fps with 40 grain v-max's and Varget, a little below listed max load. A 22-250 ai is a tiny bit more than a 22 creed, and I hear 150-200 fps is a pretty common increase over the standard 22-250, so 4310-4360. Take away 100-200 fps for the 22" barrel, that puts you 4110-4260, take away 25-50 fps for being a shade behind the 22-250ai in average, and your 22 creed is at 4060 on the slow side and 4235 on the higher side. That is how I would form my expectations.
In other words, yes, it will be very flat. Zero at 325, and it keeps you within about 3.5" of POA out to 375 yards