I would agree that one can can cover multiple calibers, with the caveat of them all being centerfire. I have three small bore cans, one is exclusively used on a 17HMR, the other two are .22 only, and I wouldn't want to try cleaning what comes out of them out of a sealed can. The main reason rimfire cans exist is serviceability, the secondary reason is rimfires don't need a lot of volume to suppress the round so they tend to be a lot smaller.
Cost is $550 including the stamp for a SiCo Sparrow 22, that's less than a half-decent rifle scope. And it's half the size and weight of a 30 cal can. There's just no need for a sealed, 30 cal capable can on a rimfire. It's like buying a Peterbilt to tow a popup camper, the downsides outweigh the benefits because it's too massively overkill for the job. I squirrel hunt with rimfires, I don't want or need a 12oz can hanging off the end of the barrel, it would really screw up the balance of a rimfire rifle. I would shoot unsuppressed before using a centerfire caliber can on a rimfire rifle, and I'm a whore for suppressors.
Quick edit - I use a TBAC 338 Ultra on one specific 300 Blackout. I'm no stranger to massive overkill, and still wouldn't put a 30 cal can on a rimfire.