I think you would do well being able to confidently shoot to 500 but can definitely stalk a lot closer. Last year my shot was at 119 in pretty open country except one small hill, year before 427 in good stalking county.
I'm not saying one should shoot antelope at 600 + yards but I do believe practice at distance improves your odds at reasonable hunting distance. I believe a hundred rounds or so at 600 plus means a dicent 3-400 yard shot on game.
I play a lot at distance, this is an 18 in wide target at 684 yards with my 6.5 CM (130 gr Sierra Game changer) the first (left) shot was my poor wind call, the next 4 were a bit less then 4 inches.