I mix powder lots all the time. One container gets too low to make enough ammo out of, and below the pickup level of my Chargemaster 1500...So I'll pour what's left of one into the new lot, then mix them up VERY thoroughly (Marking my new container as a "Mixed Lot" so I know it has been blended). Chances are that if there's not much of 1 lot, and a whole new container of the other, then it will mix just fine and you're rifle might not even notice the difference.
However, it's always good to do a quick 3-shot group to check. Or run a quick ladder test just to be positive as to whether or not it affected the burn rate, and might have caused a difference in accuracy.