Because of its slow burn rate, I think you'll find that your RL-25 will give you large ES numbers. Not an issue if you're not shooting past 500 yards but will become problematic at longer distances. If you want accuracy at any distance (and temperature), nothing will beat H4350. My personal load develops 2803fps m/v and 6fps ES. It shoots .25MOA out of a GA Precission custom rifle with a 26" Bartlein barrel. My load is as follows:
Lapua Brass
CCI450 Primers
42.0gn H4350
Berger 140gn Hybrid Target
.002 neck tension
CBTO 2.234 (-.010 off the lands)
I recommend starting at 40.0gn and working up in .2 or .3gn increments, until you find your rifle's accuracy node.
Hope this helps.