The 300 win and 300 WBY are excellent for moose. Suggest use a good bonded bullet like the Swift A frame or Nosler Part. The 338 Win or 338 RUM seems to destroys less meat using the same bullets in 225gr. I am a big fan of the 300 Win, 338 Win and 338 RUM for moose hunting. This 2016 moose season I will hunting with my Custom Rem 700 XCR 2 in 338 RUM with swift A frames 225gr.