I shoot a 280! I shoot a 280! It's my primary carry-rifle for deer hunting.
http://www.longrangehunting.com/forums/f53/my-280-updated-32771/
Load data might be included on that thread. Can't exactly remember. Off the top of my head though, I shoot the 168vld with 56grains H4831 lit by a Winchester primer. I get 2780fps with that load out of a 24" barrel.
A buddy of mine shoots the 180grain Berger hybrids in his 284win and he loads it with some amount of H4350 and gets outstanding velocities (can't recall right now though). Suffice to say that his results have me thinking of redeveloping my load with H4350.
Generally speaking, I am not a fan of the Reloder powders as they are not very temp stable whereas the Hodgdon powders are.