Bear, I just had my first custom rifle built in a 6.5-06. It sports a 29 inch barrel, 8.5x25x50 Luey LRT scope, weighing in at 13 lbs. The stock was measured to size for my short reach and I had a muzzlebrake designed by the 'smith. I swear when I am shooting it, it feels like an air gun firing pellets.
I'm a little guy and the first shot I ever took with a scoped rifle placed a half moon directly over my eye which I still wear proudly. As a result, I have always been a bit recoil shy. I have gotten over it to a degree but it still lurks in my mind when shooting my hunting rifles at the range that do not wear a brake.
I believe having a stock fitted properly, a muzzlebrake installed, a high quality recoil pad installed, proper shooting technique (which i am sill working on), and proper bench equipment, you should have no problem with any of the calibers mentioned above. I know muzzlebrakes aren't the most popular to people sitting next to you, but if you have never shot a rifle with one, I think you would be amazed at the reduction in recoil that they alone will provide. Good luck with your surgery, i hope it helps! Jim R