If you had to have only three?

[Brewer]

if I were making an economical choice they would be:
.223
.308
.30-06

If they were to cover all basis (like every animal on the planet) and money was not an issue:

.22-250 AI
6.5mm-06 AI
338 Lapua

My Favorites:
.22-250 IA
6.5-06 AI
300 WM

 

[MontanaMarine]

I could be pretty happy with three 308 Win's,

- Sporter
- Heavy precision boltgun
- AR-10 18" carbine.

 

[Trever]

22-250
270 win
12 ga

 

[justgoto]

7.62x39
30-30
30-06

 

[tony m]

How about 220 swift, 270 win and a 375 h&h....Intercontinental!

 

[7 loader]

22-250, 7mm rem mag, and a 460 Weatherby.

 

[Jim in Cali]

22-250
257 Weatherby
340 Weatherby

 

[Dgd6mm]

.22-250, 7-08, .300 wsm

 

[dmj]

22-250
7mmstw
300rum

 

[Panchik]

- 243win - varmint
- 308win
- 300wm
Now I have 308 and 300wm and actually they do any job well from varmint to big game depending on optic.
I think 243 win could be good addition to what I have. I would use it for target shooting and varmint hunting. For this purpose I have great NF 5.5-22x56

 

[Creedmoor shooter]

223 rem.
6.5 Creedmoor
7mm RM

 

[inkballedtarget]

220 swift
7 saum
338 Norma mag

 

[fisherman983]

22-250

264 win mag.

don't need a 3rd, the 264 will do everything I will ever need it to.

 

[crittrgittr]

22-250
270 wsm
300 winmag