Just depends. Me, 25 feet to 980 yards so far. No telling what is going to happen out there. I just pack a 6 or 6.5 and it covers the bases. Currently it’s a 6.5 prc.Personally I don't have any experience with the proper rifle for wolves but I could reasonably say that anything from a good .224 cartridge thru the 284s would suffice as great wolf cartridges. The flatter the better as I understand they aren't an animal you'll likely shoot up close.