I'm in the house and don't have my loading data, but I've loaded 350gr Hornady jacketed round nose bullets to 3100 fps with no pressure signs. Even with the lousy B/C, they ought to get it done out to 300-400 yds. I've also loaded 400gr Barnes X's (that I moly coated). No pressure signs either. Never chronographed them, but would expect 2800-2900 fps easy. They definitely would get it done, probably out to 500 yds.
I've shot three 460's and all had the integral brake. Recoil was stated by Wby to be 82 ft/lbs with the old elephant box 500gr ammo. On the bench, they get tedious after 3-4 rounds. The 350gr handloads were pussycats. Lots of fun, and cheap to shoot, (relatively). The 400's were fun also. With an Accubrake, recoil should be down to 50 - 60 ft/lbs with the factory 500's, and much less with lighter bullets. Factory ammo and brass are very expensive, so be prepared.
Once you shoot one, the rest get a little boring. I've never hunted with one, but wouldn't hesitate to do so. One very important caution: use a scope with at least 3.5" of eye relief. 4" is better. It is sometimes hard to keep it from tapping your eyebrow!
My choice for Elk would be a .340 Wby at about 9 - 10 lbs scoped, with 250gr Nosler Partitions, but if I wanted a .460, I wouldn't settle for anything else and I would hunt with it.