I did not see any reference where the OP was asking about the 225 gr being used in a 338 AM but just for everyones information, I do not recommend that bullet weight in the 338 Allen Magnum. To light for proper powder ignition.
In my testing, even the 250 gr bullet weights are pretty light for good powder ignition. At 265 gr you really start to see good performance, 280 gr even better, 300 gr great!!!
To the OPs question, it all depends on chambering and distance. The SST in a moderate sized magnum may be to fragile for hard impacts at ranges under 300 yards but at ranges past say 600 yards would perform completely different.
I would also agree the Interbond would be a bit better choice but still would avoid really hard close range impacts like shoulder knuckles and such. The Nosler Accubond is a stouter bullet simply because it has a much heavier jacket and heavy solid base compared to the Interbond which has a relatively thin jacket. Yes its bonded but the jacket thickness will still determine how the bullet will penetrate under hard impacts.
I would prefer to see a bit more bullet weight such as the 250 gr but there is no question that a well placed 225 gr bullet will do anything you need to do, many of you will remember the adventures of old GoodGrouper and the 225 gr Accubond was about the only bullet he used in his 338 Thunder (338 RUM improved).